/**
 * ThrombIA Design System v1.0
 * Sistema de diseño modular y accesible
 * Cumplimiento: WCAG 2.1 AA
 */

/* ==================== CSS VARIABLES ==================== */
:root {
    /* Colores principales */
    --thrombia-primary: #2563eb;
    --thrombia-primary-hover: #1d4ed8;
    --thrombia-primary-light: #dbeafe;
    --thrombia-secondary: #059669;
    --thrombia-secondary-hover: #047857;

    /* Colores semánticos */
    --color-success: #10b981;
    --color-success-bg: #d1fae5;
    --color-warning: #f59e0b;
    --color-warning-bg: #fef3c7;
    --color-error: #ef4444;
    --color-error-bg: #fee2e2;
    --color-info: #3b82f6;
    --color-info-bg: #dbeafe;

    /* Grises (con buen contraste) */
    --gray-50: #f9fafb;
    --gray-100: #f3f4f6;
    --gray-200: #e5e7eb;
    --gray-300: #d1d5db;
    --gray-400: #9ca3af;
    --gray-500: #6b7280;
    --gray-600: #4b5563;
    --gray-700: #374151;
    --gray-800: #1f2937;
    --gray-900: #111827;

    /* Tipografía */
    --font-family: 'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;
    --font-mono: 'JetBrains Mono', 'Fira Code', monospace;

    /* Tamaños de fuente */
    --text-xs: 0.75rem;
    --text-sm: 0.875rem;
    --text-base: 1rem;
    --text-lg: 1.125rem;
    --text-xl: 1.25rem;
    --text-2xl: 1.5rem;
    --text-3xl: 1.875rem;

    /* Espaciado */
    --space-1: 0.25rem;
    --space-2: 0.5rem;
    --space-3: 0.75rem;
    --space-4: 1rem;
    --space-5: 1.25rem;
    --space-6: 1.5rem;
    --space-8: 2rem;
    --space-10: 2.5rem;
    --space-12: 3rem;

    /* Bordes */
    --radius-sm: 0.25rem;
    --radius-md: 0.375rem;
    --radius-lg: 0.5rem;
    --radius-xl: 0.75rem;
    --radius-2xl: 1rem;
    --radius-full: 9999px;

    /* Sombras */
    --shadow-sm: 0 1px 2px 0 rgb(0 0 0 / 0.05);
    --shadow-md: 0 4px 6px -1px rgb(0 0 0 / 0.1), 0 2px 4px -2px rgb(0 0 0 / 0.1);
    --shadow-lg: 0 10px 15px -3px rgb(0 0 0 / 0.1), 0 4px 6px -4px rgb(0 0 0 / 0.1);
    --shadow-xl: 0 20px 25px -5px rgb(0 0 0 / 0.1), 0 8px 10px -6px rgb(0 0 0 / 0.1);

    /* Transiciones */
    --transition-fast: 150ms ease;
    --transition-base: 200ms ease;
    --transition-slow: 300ms ease;

    /* Z-index */
    --z-dropdown: 100;
    --z-sticky: 200;
    --z-modal: 300;
    --z-tooltip: 400;
    --z-toast: 500;
}

/* ==================== RESET Y BASE ==================== */
*, *::before, *::after {
    box-sizing: border-box;
    margin: 0;
    padding: 0;
}

html {
    font-size: 16px;
    -webkit-font-smoothing: antialiased;
    -moz-osx-font-smoothing: grayscale;
}

body {
    font-family: var(--font-family);
    font-size: var(--text-base);
    line-height: 1.5;
    color: var(--gray-800);
    background-color: var(--gray-50);
}

/* Focus visible para accesibilidad */
:focus-visible {
    outline: 2px solid var(--thrombia-primary);
    outline-offset: 2px;
}

/* ==================== TIPOGRAFÍA ==================== */
.text-xs { font-size: var(--text-xs); }
.text-sm { font-size: var(--text-sm); }
.text-base { font-size: var(--text-base); }
.text-lg { font-size: var(--text-lg); }
.text-xl { font-size: var(--text-xl); }
.text-2xl { font-size: var(--text-2xl); }
.text-3xl { font-size: var(--text-3xl); }

.font-normal { font-weight: 400; }
.font-medium { font-weight: 500; }
.font-semibold { font-weight: 600; }
.font-bold { font-weight: 700; }

.text-muted { color: var(--gray-500); }
.text-primary { color: var(--thrombia-primary); }
.text-success { color: var(--color-success); }
.text-warning { color: var(--color-warning); }
.text-error { color: var(--color-error); }

/* ==================== BOTONES ==================== */
.btn {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    gap: var(--space-2);
    padding: var(--space-2) var(--space-4);
    font-family: inherit;
    font-size: var(--text-sm);
    font-weight: 500;
    line-height: 1.5;
    text-decoration: none;
    border: 1px solid transparent;
    border-radius: var(--radius-md);
    cursor: pointer;
    transition: all var(--transition-fast);
    white-space: nowrap;
}

.btn:disabled {
    opacity: 0.5;
    cursor: not-allowed;
}

/* Variantes de botón */
.btn-primary {
    background-color: var(--thrombia-primary);
    color: white;
}

.btn-primary:hover:not(:disabled) {
    background-color: var(--thrombia-primary-hover);
}

.btn-secondary {
    background-color: var(--gray-100);
    color: var(--gray-700);
    border-color: var(--gray-300);
}

.btn-secondary:hover:not(:disabled) {
    background-color: var(--gray-200);
}

.btn-success {
    background-color: var(--color-success);
    color: white;
}

.btn-success:hover:not(:disabled) {
    background-color: var(--thrombia-secondary-hover);
}

.btn-danger {
    background-color: var(--color-error);
    color: white;
}

.btn-danger:hover:not(:disabled) {
    background-color: #dc2626;
}

.btn-outline {
    background-color: transparent;
    border-color: var(--gray-300);
    color: var(--gray-700);
}

.btn-outline:hover:not(:disabled) {
    background-color: var(--gray-100);
}

.btn-ghost {
    background-color: transparent;
    color: var(--gray-600);
}

.btn-ghost:hover:not(:disabled) {
    background-color: var(--gray-100);
}

/* Tamaños de botón */
.btn-sm {
    padding: var(--space-1) var(--space-3);
    font-size: var(--text-xs);
}

.btn-lg {
    padding: var(--space-3) var(--space-6);
    font-size: var(--text-base);
}

.btn-icon {
    padding: var(--space-2);
    width: 36px;
    height: 36px;
}

/* ==================== INPUTS ==================== */
.form-group {
    margin-bottom: var(--space-4);
}

.form-label {
    display: block;
    margin-bottom: var(--space-1);
    font-size: var(--text-sm);
    font-weight: 500;
    color: var(--gray-700);
}

.form-label-required::after {
    content: " *";
    color: var(--color-error);
}

.form-input,
.form-select,
.form-textarea {
    width: 100%;
    padding: var(--space-2) var(--space-3);
    font-family: inherit;
    font-size: var(--text-sm);
    line-height: 1.5;
    color: var(--gray-800);
    background-color: white;
    border: 1px solid var(--gray-300);
    border-radius: var(--radius-md);
    transition: border-color var(--transition-fast), box-shadow var(--transition-fast);
}

.form-input:focus,
.form-select:focus,
.form-textarea:focus {
    border-color: var(--thrombia-primary);
    box-shadow: 0 0 0 3px var(--thrombia-primary-light);
    outline: none;
}

.form-input::placeholder {
    color: var(--gray-400);
}

.form-input-error {
    border-color: var(--color-error);
}

.form-input-error:focus {
    box-shadow: 0 0 0 3px var(--color-error-bg);
}

.form-hint {
    margin-top: var(--space-1);
    font-size: var(--text-xs);
    color: var(--gray-500);
}

.form-error {
    margin-top: var(--space-1);
    font-size: var(--text-xs);
    color: var(--color-error);
}

/* ==================== CARDS ==================== */
.card {
    background-color: white;
    border: 1px solid var(--gray-200);
    border-radius: var(--radius-lg);
    box-shadow: var(--shadow-sm);
    overflow: hidden;
}

.card-header {
    padding: var(--space-4) var(--space-5);
    border-bottom: 1px solid var(--gray-200);
    background-color: var(--gray-50);
}

.card-title {
    font-size: var(--text-lg);
    font-weight: 600;
    color: var(--gray-900);
}

.card-subtitle {
    margin-top: var(--space-1);
    font-size: var(--text-sm);
    color: var(--gray-500);
}

.card-body {
    padding: var(--space-5);
}

.card-footer {
    padding: var(--space-4) var(--space-5);
    border-top: 1px solid var(--gray-200);
    background-color: var(--gray-50);
}

/* ==================== BADGES ==================== */
.badge {
    display: inline-flex;
    align-items: center;
    padding: var(--space-1) var(--space-2);
    font-size: var(--text-xs);
    font-weight: 500;
    border-radius: var(--radius-full);
}

.badge-primary {
    background-color: var(--thrombia-primary-light);
    color: var(--thrombia-primary);
}

.badge-success {
    background-color: var(--color-success-bg);
    color: #065f46;
}

.badge-warning {
    background-color: var(--color-warning-bg);
    color: #92400e;
}

.badge-error {
    background-color: var(--color-error-bg);
    color: #991b1b;
}

.badge-info {
    background-color: var(--color-info-bg);
    color: #1e40af;
}

/* ==================== ALERTAS ==================== */
.alert {
    display: flex;
    align-items: flex-start;
    gap: var(--space-3);
    padding: var(--space-4);
    border-radius: var(--radius-lg);
    margin-bottom: var(--space-4);
}

.alert-icon {
    flex-shrink: 0;
    width: 20px;
    height: 20px;
}

.alert-content {
    flex: 1;
}

.alert-title {
    font-weight: 600;
    margin-bottom: var(--space-1);
}

.alert-success {
    background-color: var(--color-success-bg);
    border: 1px solid #a7f3d0;
    color: #065f46;
}

.alert-warning {
    background-color: var(--color-warning-bg);
    border: 1px solid #fcd34d;
    color: #92400e;
}

.alert-error {
    background-color: var(--color-error-bg);
    border: 1px solid #fca5a5;
    color: #991b1b;
}

.alert-info {
    background-color: var(--color-info-bg);
    border: 1px solid #93c5fd;
    color: #1e40af;
}

/* ==================== TABS ==================== */
.tabs {
    display: flex;
    gap: var(--space-1);
    border-bottom: 1px solid var(--gray-200);
}

.tab {
    padding: var(--space-3) var(--space-4);
    font-size: var(--text-sm);
    font-weight: 500;
    color: var(--gray-500);
    background: none;
    border: none;
    border-bottom: 2px solid transparent;
    cursor: pointer;
    transition: all var(--transition-fast);
}

.tab:hover {
    color: var(--gray-700);
}

.tab[aria-selected="true"],
.tab.active {
    color: var(--thrombia-primary);
    border-bottom-color: var(--thrombia-primary);
}

.tab-panel {
    display: none;
    padding: var(--space-4);
}

.tab-panel.active {
    display: block;
}

/* ==================== MODALES ==================== */
.modal-overlay {
    position: fixed;
    inset: 0;
    background-color: rgba(0, 0, 0, 0.5);
    display: flex;
    align-items: center;
    justify-content: center;
    z-index: var(--z-modal);
    opacity: 0;
    visibility: hidden;
    transition: all var(--transition-base);
}

.modal-overlay.active {
    opacity: 1;
    visibility: visible;
}

.modal {
    background-color: white;
    border-radius: var(--radius-xl);
    box-shadow: var(--shadow-xl);
    max-width: 500px;
    width: 90%;
    max-height: 90vh;
    overflow: auto;
    transform: scale(0.95);
    transition: transform var(--transition-base);
}

.modal-overlay.active .modal {
    transform: scale(1);
}

.modal-header {
    display: flex;
    align-items: center;
    justify-content: space-between;
    padding: var(--space-4) var(--space-5);
    border-bottom: 1px solid var(--gray-200);
}

.modal-title {
    font-size: var(--text-lg);
    font-weight: 600;
}

.modal-close {
    padding: var(--space-2);
    background: none;
    border: none;
    color: var(--gray-400);
    cursor: pointer;
    border-radius: var(--radius-md);
    transition: all var(--transition-fast);
}

.modal-close:hover {
    background-color: var(--gray-100);
    color: var(--gray-600);
}

.modal-body {
    padding: var(--space-5);
}

.modal-footer {
    display: flex;
    justify-content: flex-end;
    gap: var(--space-3);
    padding: var(--space-4) var(--space-5);
    border-top: 1px solid var(--gray-200);
    background-color: var(--gray-50);
}

/* ==================== PROGRESS & LOADING ==================== */
.progress {
    width: 100%;
    height: 8px;
    background-color: var(--gray-200);
    border-radius: var(--radius-full);
    overflow: hidden;
}

.progress-bar {
    height: 100%;
    background-color: var(--thrombia-primary);
    border-radius: var(--radius-full);
    transition: width var(--transition-slow);
}

.progress-bar-animated {
    animation: progress-stripes 1s linear infinite;
    background-image: linear-gradient(
        45deg,
        rgba(255, 255, 255, 0.15) 25%,
        transparent 25%,
        transparent 50%,
        rgba(255, 255, 255, 0.15) 50%,
        rgba(255, 255, 255, 0.15) 75%,
        transparent 75%,
        transparent
    );
    background-size: 1rem 1rem;
}

@keyframes progress-stripes {
    from { background-position: 1rem 0; }
    to { background-position: 0 0; }
}

/* Spinner */
.spinner {
    width: 24px;
    height: 24px;
    border: 3px solid var(--gray-200);
    border-top-color: var(--thrombia-primary);
    border-radius: 50%;
    animation: spin 0.8s linear infinite;
}

.spinner-sm {
    width: 16px;
    height: 16px;
    border-width: 2px;
}

.spinner-lg {
    width: 40px;
    height: 40px;
    border-width: 4px;
}

@keyframes spin {
    to { transform: rotate(360deg); }
}

/* Loading overlay */
.loading-overlay {
    position: absolute;
    inset: 0;
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: center;
    gap: var(--space-3);
    background-color: rgba(255, 255, 255, 0.9);
    z-index: var(--z-modal);
}

.loading-text {
    font-size: var(--text-sm);
    color: var(--gray-600);
}

/* ==================== TOASTS ==================== */
.toast-container {
    position: fixed;
    bottom: var(--space-6);
    right: var(--space-6);
    display: flex;
    flex-direction: column;
    gap: var(--space-3);
    z-index: var(--z-toast);
}

.toast {
    display: flex;
    align-items: flex-start;
    gap: var(--space-3);
    padding: var(--space-4);
    background-color: white;
    border-radius: var(--radius-lg);
    box-shadow: var(--shadow-lg);
    min-width: 300px;
    max-width: 400px;
    animation: toast-in 0.3s ease;
}

.toast-leaving {
    animation: toast-out 0.3s ease forwards;
}

@keyframes toast-in {
    from {
        opacity: 0;
        transform: translateX(100%);
    }
    to {
        opacity: 1;
        transform: translateX(0);
    }
}

@keyframes toast-out {
    from {
        opacity: 1;
        transform: translateX(0);
    }
    to {
        opacity: 0;
        transform: translateX(100%);
    }
}

/* ==================== TABLES ==================== */
.table-container {
    overflow-x: auto;
    border: 1px solid var(--gray-200);
    border-radius: var(--radius-lg);
}

.table {
    width: 100%;
    border-collapse: collapse;
    font-size: var(--text-sm);
}

.table th,
.table td {
    padding: var(--space-3) var(--space-4);
    text-align: left;
    border-bottom: 1px solid var(--gray-200);
}

.table th {
    background-color: var(--gray-50);
    font-weight: 600;
    color: var(--gray-700);
}

.table tbody tr:hover {
    background-color: var(--gray-50);
}

.table tbody tr:last-child td {
    border-bottom: none;
}

/* ==================== SCORES MÉDICOS ==================== */
.score-card {
    display: flex;
    flex-direction: column;
    padding: var(--space-4);
    background: white;
    border: 1px solid var(--gray-200);
    border-radius: var(--radius-lg);
}

.score-header {
    display: flex;
    justify-content: space-between;
    align-items: center;
    margin-bottom: var(--space-3);
}

.score-name {
    font-weight: 600;
    color: var(--gray-800);
}

.score-value {
    font-size: var(--text-2xl);
    font-weight: 700;
}

.score-value-low { color: var(--color-success); }
.score-value-moderate { color: var(--color-warning); }
.score-value-high { color: var(--color-error); }

.score-interpretation {
    font-size: var(--text-sm);
    color: var(--gray-600);
    margin-top: var(--space-2);
}

.score-action {
    margin-top: var(--space-3);
    padding-top: var(--space-3);
    border-top: 1px solid var(--gray-200);
    font-size: var(--text-sm);
}

/* ==================== LAYOUT HELPERS ==================== */
.container {
    width: 100%;
    max-width: 1280px;
    margin: 0 auto;
    padding: 0 var(--space-4);
}

.flex { display: flex; }
.flex-col { flex-direction: column; }
.items-center { align-items: center; }
.items-start { align-items: flex-start; }
.justify-between { justify-content: space-between; }
.justify-center { justify-content: center; }
.gap-2 { gap: var(--space-2); }
.gap-3 { gap: var(--space-3); }
.gap-4 { gap: var(--space-4); }

.grid { display: grid; }
.grid-cols-2 { grid-template-columns: repeat(2, 1fr); }
.grid-cols-3 { grid-template-columns: repeat(3, 1fr); }
.grid-cols-4 { grid-template-columns: repeat(4, 1fr); }

.hidden { display: none !important; }
.sr-only {
    position: absolute;
    width: 1px;
    height: 1px;
    padding: 0;
    margin: -1px;
    overflow: hidden;
    clip: rect(0, 0, 0, 0);
    white-space: nowrap;
    border: 0;
}

/* ==================== RESPONSIVE ==================== */
@media (max-width: 768px) {
    :root {
        --text-base: 0.9375rem;
    }

    .container {
        padding: 0 var(--space-3);
    }

    .grid-cols-2,
    .grid-cols-3,
    .grid-cols-4 {
        grid-template-columns: 1fr;
    }

    .modal {
        width: 95%;
        margin: var(--space-4);
    }

    .tabs {
        overflow-x: auto;
        -webkit-overflow-scrolling: touch;
    }

    .tab {
        padding: var(--space-2) var(--space-3);
        white-space: nowrap;
    }

    .toast-container {
        left: var(--space-4);
        right: var(--space-4);
        bottom: var(--space-4);
    }

    .toast {
        min-width: auto;
        max-width: none;
    }
}

@media (min-width: 768px) and (max-width: 1024px) {
    .grid-cols-4 {
        grid-template-columns: repeat(2, 1fr);
    }
}

/* ==================== ANIMACIONES ==================== */
.fade-in {
    animation: fadeIn var(--transition-base);
}

@keyframes fadeIn {
    from { opacity: 0; }
    to { opacity: 1; }
}

.slide-up {
    animation: slideUp var(--transition-base);
}

@keyframes slideUp {
    from {
        opacity: 0;
        transform: translateY(10px);
    }
    to {
        opacity: 1;
        transform: translateY(0);
    }
}

/* ==================== PRINT ==================== */
@media print {
    .no-print {
        display: none !important;
    }

    body {
        background: white;
        color: black;
    }

    .card {
        box-shadow: none;
        border: 1px solid #ccc;
    }
}